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apalutamide will minimize the level or result of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of apalutamide, a robust CYP3A4 inducer, with medications which might be CYP3A4 substrates may result in lower exposure to these prescription drugs.The regulation of modafinil as
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